Effect of Glucose upon Alkaline Picrate: A Jaffé Interference
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چکیده
منابع مشابه
Glucose interference in Jaffé creatinine method: effect of calcium from peritoneal dialysate.
2326 CUNICAL CHEMISTRY, Vol.40,No. 12,1994 of serum specimens contaminated with heparin (from indwelling lines) into heparin-containing Vacutainer Tubes (Becton Dickinson, Rutherford, NJ), and (b) by adding heparin (final concentration, 25-SO kIUIL) to the diluent used on the Tosoh AIA1200. The results are shown in Table 1. Interference was judged to be eliminated if triplicates were no longer ...
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A patient who ingested a methanol/nitromethane mixture (model airplane fuel) showed an apparent plasma creatinine concentration of 8.0 mmol/L by the Jaffé reaction when the actual creatinine concentration, as measured by a specific enzymatic method, was 0.09 mmol/L. This effect was due to nitromethane in the plasma. Interference by nitromethane with the determination of creatinine by reaction w...
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Bilirubin causes underestimation of serum creatinine in the Jaffé alkaline picrate assay. We report an approach for preventing bilirubin interference by pretreating serum samples with peroxidase and H2O2. The dissociation of bilirubin from albumin and its subsequent oxidation markedly reduces the bilirubin interference and enables accurate determination of creatinine concentrations by the Jaffé...
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Cephaloglycin, cephalothin, cephaloridine, cefoxitin, and cephacetrile are cephalosporin antibiotics that react with alkaline picrate solution to give a creatinine-like response. The mechanism of this reaction is not known, and several structurally similar compounds do not react under these same conditions. Because large quantities of a cephalosporin antibiotic may be administered to a patient ...
متن کاملLactulose interferes in the alkaline picrate assay for creatinine.
Errors of more than 10 mg/L in measured serum creatinine concentrations were encountered for an azotemic patient who was given lactulose orally. The magnitude of the apparent error fluctuated with the dose of lactulose. Additions of lactulose to serum produced a linear increase in the creatinine measured by each of two automated methods that involve use of the alkaline picrate (Jaffé) reaction....
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine
سال: 1990
ISSN: 1434-6621,1437-4331
DOI: 10.1515/cclm.1990.28.2.95